Based on a novel of the same name. The mitochondria within Eve have revolted and taken over. You play as Aya Brea who must hunt her down before she takes over the world. Kill mitochondria-possessed creatures like rats, dogs, alligators, dinosaur skeletons, etc. Gain new abilities like pyrokenesis, and level up your weapons and armor.

Takes place on Manhattan Island, NY over the course of 6 days, starting on Christmas Eve as Aya goes on a date to the opera where Eve makes her debut by igniting the audience.